Annual report [Section 13 and 15(d), not S-K Item 405]

SHARE-BASED COMPENSATION - Statements of operations (Details)

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SHARE-BASED COMPENSATION - Statements of operations (Details) - USD ($)
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
SHARE-BASED COMPENSATION    
Total share-based compensation $ 857,628 $ 825,808
Research and development    
SHARE-BASED COMPENSATION    
Total share-based compensation 37,674 49,405
General and administrative    
SHARE-BASED COMPENSATION    
Total share-based compensation $ 819,954 $ 776,403