Exhibit 16.1



July 28, 2022


Securities and Exchange Commission
100 F Street, N.E.
Washington DC 20549




We have read the statements made by ProMIS Neurosciences Inc. (copy attached), which we understand will be included under Item 4.01 of Form 8-K which will be filed with the Securities and Exchange Commission on July 29, 2022. We agree with the statements concerning our Firm contained therein.


Very truly yours,



Chartered Professional Accountants, Licensed Public Accountants


Oakville, Canada